منابع مشابه
Chemokines in inflammatory bowel diseases.
Uncontrolled activation of mucosal effector cells has been identified as the main pathogenic mechanism involved in the initiation and perpetuation of mucosal inflammation in inflammatory bowel diseases (IBD). The sustained activation of these cells leads to the aberrant production of various pro-inflammatory mediators, which co-ordinated action amplifies the inflammatory process. In this settin...
متن کاملChemokines in inflammatory bowel disease.
C hemokines (chemotactic cytokines) are small (7–10 kDa) heparin binding proteins that govern the migration of circulating leucocytes to the sites of inflammation. Chemokines, currently numbering more than 50, are classified into four supergene families based on cysteine residues: CXC, CC, C, and CX3C chemokines (table 1). Chemokines are distinguished from other cytokines by acting on the G pro...
متن کامل[Inflammatory bowel diseases]
OBJECTIVE: To present a review about inflammatory bowel diseases in childhood so that pediatricians become familiar with two diseases (ulcerative colitis and Crohn s disease) that are increasing in incidence. METHODS: Articles of specific gastroenterological journals were analyzed. Information was also obtained from the author s extensive professional experience in the area. RESULTS: The two di...
متن کاملInflammatory bowel diseases.
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متن کاملInflammatory Bowel Diseases Journal
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ژورنال
عنوان ژورنال: Digestive Diseases
سال: 2010
ISSN: 1421-9875,0257-2753
DOI: 10.1159/000320392